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James A. Knost, M.D.
Education
Dr. Knost graduated from Louisiana State University in Baton Rouge, Louisiana, and attended Louisiana State Medical Center in New Orleans, Louisiana. His internship and residency were done in internal medicine at Vanderbilt University Hospital in Nashville, Tennessee. He then did a medical oncology fellowship at Vanderbilt.

Medical Specialties
Areas of specialty within practice: colon, head/neck, prostate, renal, ureter, bladder and GI non-colon

Board Certification
Internal Medicine and Medical Oncology

Work History
Dr. Knost was an assistant professor in medical oncology at West Virginia Medical Center at Morgantown, West Virginia. This was followed by two years as an expert appointment at the National Cancer Institute’s Biological Modifier Response Program (monoclonal antibody section) at Frederick Cancer Research Facility in Fort Detrick, Frederick, Maryland.

When did you join Illinois CancerCare?
1992

Illinois CancerCare Clinic Affiliation
Peoria, Spring Valley and Peru

Family Information
Dr. Knost was born in Joplin, Missouri, and now resides in Peoria with his wife and family.

Hobbies/Interests
Grandchildren, gardening and fly-fishing

What medical change has impacted the field of cancer the most since you began practicing medicine?
“The change from empiricism — i.e., from just trying a drug to see if it worked — to knowing how cancer cells operate and trying to interfere with selective pathways.”

Why did you choose oncology?
“I just enjoyed taking care of patients with cancer and felt at the time — and still feel — that there is a potential to cure the majority of patients with solid malignancies.”

Why did you choose Peoria, Illinois, to practice when you could have gone anywhere in the country?
“The people of central Illinois.”

Do you have any advice to give patients after they have been diagnosed with cancer?
“With few exceptions, I think you should remember that most cancers spread very slowly and, in almost all cases, there is time to get more information about your disease and to seek a first and second opinion if you are unsure about what you want to do with regard to therapy.”

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